2 Articles by David Nutt
Neuroplasticity and Psychedelics: A comprehensive examination of classic and non-classic compounds in pre and clinical models.
Neuroscience and biobehavioral reviews – April 02, 2025
Summary
Psychedelics may reshape our understanding of brain health, showing promise in treating mood disorders by enhancing functional and structural neuroplasticity. Research indicates these compounds boost the nervous system's adaptability, fostering long-term changes that could revolutionize therapeutic approaches. Exciting advancements in imaging techniques are paving the way for deeper insights into their potential.
Abstract
Neuroplasticity, the ability of the nervous system to adapt throughout an organism's lifespan, offers potential as both a biomarker and treatment t...
Transient destabilization of whole brain dynamics induced by N,N-Dimethyltryptamine (DMT).
Communications biology – March 11, 2025
Summary
Psychedelics can rapidly alter brain dynamics, creating heightened states of awareness. In a study with 15 participants, researchers simulated brain activity during DMT exposure, revealing a temporary surge in reactivity, especially in areas tied to perception and cognition. This insight enhances our understanding of how brief psychedelic experiences can leave lasting impressions.
Abstract
The transition towards the brain state induced by psychedelic drugs is frequently neglected in favor of a static description of their acute effects...