1 Article by Jonathan Repple

Current evidence for the role of rapid-acting antidepressants (RAAD) in bipolar depression? A perspective and plan for action.

Biological psychiatry – March 08, 2025

Summary

Recent advancements in rapid-acting antidepressants (RAADs) offer hope for treating bipolar depression, a condition often overlooked. These treatments, including NMDA antagonists like ketamine, show promise in enhancing recovery by targeting glutamate pathways. Expanding research in this area could significantly improve outcomes for those struggling with bipolar disorder.

Abstract

After decades of limited progress in depression treatment, recent advancements have sparked renewed interest in developing novel antidepressants, p...

Tags

Mdd