3 Articles by Jacob S Aday
Addressing blinding in classic psychedelic studies with innovative active placebos.
The international journal of neuropsychopharmacology – April 04, 2025
Summary
Classic psychedelics show great potential for treating neuropsychiatric disorders, but weak blinding in studies can skew results. This review highlights the need for innovative active placebos that mimic drug effects without therapeutic benefits. By improving control conditions, researchers can better assess the true efficacy and safety of psychedelics.
Abstract
Classic psychedelics show promise as a treatment for various neuropsychiatric disorders. However, weak blinding integrity in trials has been argued...
Perceived Impact of Psychedelics on Sexual, Gender, and Intimate Relationship Dynamics: A Mixed-Methods Investigation.
Journal of sex research – March 28, 2025
Summary
Psychedelics have been reported to positively influence sexuality and intimate relationships, with 70% of users noting beneficial effects. Many experienced enhanced attraction and relationship quality, while some reported shifts in gender identity and sexual orientation. These substances appear to promote self-acceptance and deeper connections.
Abstract
Systematic research on the impact of psychedelic use on sexuality and intimacy remains limited. This study investigated reported effects of psyched...
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Preliminary safety and effectiveness of psilocybin-assisted therapy in adults with fibromyalgia: an open-label pilot clinical trial.
Frontiers in pain research (Lausanne, Switzerland) – January 01, 2025
Summary
In a groundbreaking pilot clinical trial, psilocybin-assisted therapy showed promising results for adults with fibromyalgia, a condition marked by widespread pain and cognitive challenges. Participants experienced significant reductions in pain severity, interference, and sleep disturbances after treatment. The therapy was well-tolerated, paving the way for future studies.
Abstract
Fibromyalgia (FM) is the prototypical nociplastic pain condition, characterized by widespread pain and issues with cognition, mood, and sleep. Curr...