2 Articles by David S Baldwin
Effects of transcranial direct current stimulation (tDCS) at different cortical targets on cognition in obsessive-compulsive disorder (OCD): an exploratory analysis.
International clinical psychopharmacology – April 04, 2025
Summary
Transcranial direct current stimulation (tDCS) shows potential in enhancing cognitive flexibility for those with obsessive-compulsive disorder (OCD). In a study involving 19 adults, tDCS targeting specific brain areas significantly improved cognitive flexibility, while sham treatment did not. This suggests tDCS could be a promising tool in OCD therapy.
Abstract
Transcranial direct current stimulation (tDCS) holds promise as a treatment for obsessive-compulsive disorder (OCD). Patients with OCD show impairm...
Expectancy Effects, Failure of Blinding Integrity, and Placebo Response in Trials of Treatments for Psychiatric Disorders: A Narrative Review.
JAMA psychiatry – March 12, 2025
Summary
Expectancy effects can significantly skew results in psychiatric clinical trials, influencing how treatments are perceived and their effectiveness. This review highlights how compromised blinding and treatment expectations can introduce bias. It suggests strategies to improve reliability, emphasizing the need for objective measures to better assess treatment outcomes.
Abstract
Expectancy effects are significant confounding factors in psychiatric randomized clinical trials (RCTs), potentially affecting the interpretation o...