1 Article by Julia Hach
Reversible tuning of membrane sterol levels by cyclodextrin in a dialysis setting.
Biophysical journal – March 25, 2025
Summary
Researchers have developed a method to adjust sterol levels in liposomes, enhancing the study of membrane proteins. By using methyl-β-cyclodextrin in a controlled environment, they effectively manage cholesterol transfer. This reversible tuning improves membrane properties, paving the way for better insights into protein behavior and function.
Abstract
Large unilamellar vesicles are popular membrane models for studying the impact of lipids and bilayer properties on the structure and function of tr...