1 Article by Denis Arikci

Motivation and retrospective appraisal of psychedelic study participation: a qualitative study in healthy volunteers.

Psychopharmacology – March 26, 2025

Summary

Healthy volunteers are increasingly drawn to participate in psychedelic trials, motivated by personal growth and the allure of substances like psilocybin, Dimethyltryptamine, Lysergic acid diethylamide, and mescaline. Participants reported positive appraisals linked to supportive relationships with researchers and immersive environments. Most felt their experiences surpassed expectations and expressed a desire for future sessions in nature with friends, highlighting the importance of setting and interpersonal connections in enhancing the psychedelic experience.

Abstract

Little is known about motives of healthy volunteers to participate in psychedelic trials and how they appraise their study experience retrospective...