1 Article by Yuange Duan

Systematic revelation and meditation on the significance of long exons using representative eukaryotic genomes.

BMC genomics – March 24, 2025

Summary

Long exons, particularly the last ones in genes, play a crucial role in gene structure across various species. Analyzing seven reference genomes, researchers found these exons often have lower GC content and fewer splicing motifs in the 3’UTR. This suggests they may hold significant regulatory roles, influenced by natural selection.

Abstract

Long exons/introns are not evenly distributed in the genome, but the biological significance of this phenomenon remains elusive. Exon properties we...