1 Article by Amanda Nelson

Intravenous psilocybin induces dose-dependent changes in functional network organization in rat cortex.

Translational psychiatry – March 25, 2025

Summary

Psilocybin, known for altering consciousness, significantly impacts brain network dynamics. In a study with rats, varying doses revealed that psilocybin disrupts theta-gamma coupling while enhancing connectivity and network density in specific brain regions. These findings highlight how psilocybin may reshape brain organization during altered states.

Abstract

Psilocybin produces an altered state of consciousness in humans and is associated with complex spatiotemporal changes in cortical networks. Given t...

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