2 Articles by Richard J Zeifman

Exploring serotonergic psychedelics as a treatment for personality disorders.

Neuropharmacology – March 11, 2025

Summary

Psychedelics like psilocybin may reshape personality traits, offering new hope for treating personality disorders. This review highlights how psychedelics could enhance self-awareness and interpersonal skills, suggesting they might effectively address the core challenges of these disorders through innovative psychotherapy approaches.

Abstract

Both psychotherapeutic interventions and pharmacological agents have demonstrated limited efficacy in the treatment of personality disorders (PDs)....

A Systematic Review of Study Design and Placebo Controls in Psychedelic Research.

Psychedelic medicine (New Rochelle, N.Y.) – March 01, 2024

Summary

Psychedelics have shown promise in mental health treatment, yet effective blinding in research is challenging due to their consciousness-altering effects. This review analyzed 50 randomized control trials on classic psychedelics, highlighting study designs that enhance placebo controls and minimize bias. Active placebos may improve outcomes, paving the way for more reliable findings.

Abstract

Effective blinding is especially challenging in randomized controlled trials (RCTs) involving psychedelics due to the inherent alterations in consc...