Psilocybin Reduces Grooming in the SAPAP3 Knockout Mouse Model of Compulsive Behaviour
bioRxiv – October 23, 2024
Source: medRxiv/bioRxiv/arXiv
Summary
Recent findings reveal that psilocybin, a psychedelic compound, effectively reduces compulsive grooming behaviors in a mouse model. This study highlights psilocybin's potential as a novel treatment for compulsive disorders, offering hope for those who struggle with current medications that often fall short and come with side effects.
Abstract
Psilocybin is a serotonergic psychedelic compound which shows promise for treating compulsive behaviours. This is particularly pertinent as compulsive disorders require research into new pharmacological treatment options as the current frontline treatments such as selective serotonin reuptake inhibitors, require chronic administration, have significant side effects, and leave almost half of the clinical population refractory to treatment.