Dynamical repertoire of brain networks in mindfulness cognitive behavioural therapy during rumination: A randomized controlled trial

medRxiv – February 04, 2025

Source: medRxiv/bioRxiv/arXiv

Summary

Mindfulness-based cognitive therapy effectively reduces depressive rumination by enhancing emotional regulation and awareness. A recent study revealed that this approach positively alters brain network dynamics, helping individuals manage their thoughts and emotions better. These findings highlight the transformative potential of mindfulness in overcoming depression.

Abstract

BACKGROUND Depression is a prevalent and debilitating affective disorder characterised by the dominance and persistence of depressive rumination. Mindfulness-based cognitive therapy (MBCT) is an effective treatment for recurrent depression developed specifically to target rumination and recurrence risk by training metacognitive awareness and adaptive attention, emotion and self-regulation skills. Yet, the underlying mechanisms by which mindfulness training impacts maladaptive depressive rumination is not well understood, and a deeper understanding of its effects on the complex brain dynamics during depressive rumination is needed.