Neural correlates of nightmares revisited: findings from large-scale fMRI cohorts
bioRxiv – July 02, 2024
Source: medRxiv/bioRxiv/arXiv
Summary
Nightmares can significantly impact daily life and mental health. This study explored how often nightmares occur and their connection to brain activity, particularly between the amygdala and prefrontal cortex, which helps regulate emotions. Findings from large groups confirmed that increased nightmare frequency is linked to distinct patterns of brain connectivity, shedding light on the neurological underpinnings of these distressing experiences.
Abstract
Study Objectives Nightmares are linked to daytime distress and psychiatric and neurological disorders. However, knowledge about the brain regions involved in nightmare production is sparse. This study aimed to examine the relationship between nightmare frequency and the functional connectivity of the amygdala with the prefrontal cortex, which is central to emotional regulation. Additionally, the study sought to replicate previous findings on the neural correlates of nightmares using two large cohorts.